Since traditional host operating system anti-fingerprinting technologies is lack of the ability of integration defense, a Network Deception based operating system Anti-Fingerprinting model (NDAF) was proposed. Firstly, basic working principle was introduced. The deception server made the fingerprint deception template. Each host dynamically changed the protocol stack fingerprint according to the fingerprint deception template, therefore the process of operating system fingerprinting by attacker was misguided. Secondly, a trust management mechanism was proposed to improve the system efficiency. Based on the different degree of threat, different deception strategies were carried out. Experiments show that NDAF makes certain influence on network efficiency, about 11% to 15%. Comparing experiments show that the anti-fingerprinting ability of NDAF is better than typical operating system anti-fingerprinting tools (OSfuscatge and IPmorph). NDAF can effectively increase the security of target network by integration defense and deception defense.